
Cocaine is an extremely addictive stimulant drug.
The powdered form of cocaine is actually a, hydrochloride salt. In this form it can be dissolved in water and injected or snorted. Crack is cocaine that has not been neutralized by an acid to make the hydrochloride salt. This form of cocaine appears as a rock crystal that can be heated and its vapors smoked. The term “crack” refers to the snapping and cracking sound it makes when heated and smoked.No matter what form cocaine is used in or how often it is used, a user can put themselves in acute cardiovascular or cerebrovascular danger and emergencies. These conditions can include stroke or heart attack, which could result in cardiac arrest or sudden death. Cocaine-related deaths are often a result of seizure followed by respiratory arrest.
Potential Health Hazards
Cocaine is a stimulant of the central nervous system. The drug inhibits and interferes with the reabsorption process of dopamine, which is the chemical messenger most often associated with pleasure. The buildup of dopamine causes continuous stimulation of receiving neurons, thus prosucing an exaggerated effect, which is associated with the euphoria commonly reported by cocaine users.
Some users of cocaine report feelings of restlessness, irritability, and anxiety. A tolerance to the “high” may develop-many addicts report that they seek but fail to achieve as much pleasure as they did from their first exposure. Some users will increase their doses to intensify and prolong the euphoric effects. While tolerance to the high can occur, users can also become more sensitive to cocaine’s anesthetic and convulsant effects without increasing the dose taken. This increased sensitivity may explain some deaths occurring after apparently low doses of cocaine.
Physical effects of cocaine use include dilated pupils, constricted blood vessels, and increased temperature, and blood pressure, heart rate, . The length of cocaine’s immediate high, which include reduced fatigue, hyperstimulation, and mental alertness, depends on the route of administration and the amount taken. The faster the absorption, the more intense the high. On the other hand, the faster the absorption, the shorter the duration of action. The high from snorting may last 15 to 30 minutes, while that from smoking may last 5 to 10 minutes. Increased use can reduce the period of time a user feels high and increases the risk of addiction.
Use of cocaine in a binge, during which the drug is taken repeatedly and at increasingly high doses, may lead to a state of increasing irritability, restlessness, and paranoia. This can result in a period of full-blown paranoid psychosis, in which the user loses touch with reality and experiences auditory hallucinations.
Other complications associated with cocaine use include disturbances in heart rhythm and heart attacks, chest pain and respiratory failure, strokes, seizures and headaches, and gastrointestinal complications such as abdominal pain and nausea. Because cocaine has a tendency to decrease appetite, many chronic users can become malnourished.
Different means of taking cocaine can produce different adverse effects. Regularly snorting cocaine, for example, can lead to loss of the sense of smell, nosebleeds, problems with swallowing, hoarseness, and a chronically runny nose. Ingesting cocaine can cause severe bowel gangrene due to reduced blood flow. People who inject cocaine can experience severe allergic reactions and, as with all injecting drug users, are at increased risk for contracting HIV and other blood-borne diseases.
Added Danger: Cocaethylene
When people mix cocaine and the consumption of alcohol, they are increasing and compounding the danger each drug poses on its own and unknowingly forming a complex chemical reaction within their bodies. NIDA-funded researchers have found that the human liver combines cocaine and alcohol and manufactures a third substance, cocaethylene, that intensifies cocaine’s euphoric effects, while potentially increasing the risk of sudden death.
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